Diseases overpower the immune system - for some such assaults there
has been no proven effective treatment. Autoimmune diseases are a family
of more than 80 chronic, and often disabling, illnesses that develop when
defects in the immune system lead the body to attack its own cells, tissues,
and organs. Some common autoimmune diseases include Multiple
Sclerosis, Type 1 Diabetes, Diabetic Wounds, Chronic Wounds, Chronic
Pain, Rheumatoid Arthritis, Chronic Plaque Psoriasis, and Lupus. It is
estimated that over 40% of all diseases are autoimmune.
In addition, Chronic Lyme disease, which is not technically an autoimmune
disease, but can mimic some of the common symptoms of Systemic Lupus
Erythematosus; various forms of Therapy Resistant Cancers; Chronic
Inflammatory Demyelinating Polyneuropathy (CIDP), which is an acquired immune-mediated inflammatory disorder of the peripheral nervous system; and Alzheimer's disease and dementia, are all looking for a cure. We believe Infeperium if used as an individual treatment or in conjunction with other available treatments, may lead to remission, and over time may may be considered a cure.
The traditional response to these diseases has been pharmaceuticals &
chemicals with toxins and negative side effects and potential habit forming
Narcotics. You only have to listen to the pharmaceutical companies TV ads
to know that the side effects are potentially as harmful as the disease.
To take the qualities and characteristics of Infeperium as a biological
response modifier (BRM) and anti-inflammatory agent and focus its
therapeutic and prophylactic benefits on chronic diseases and conditions
that have no available treatment or present treatments are ineffective.
Description of Product
Infeperium, the natural product, and Infeperium, the synthesized product,
are both a refinement of a USDA approved immunomodulator for treatment
of domestic animals. An Immunotherapeutic biological response modifier
(BRM) that functions in part through affecting the cytokine profile. They
function in both a prophylactic and therapeutic manner. BRM's modulate
and regulate the body's immune system and response without toxins or
negative events or forming habits. BRM's are a substance that can improve
the body's natural response to infection and disease. BRM's, a new drug class and an FDA category of their own, are medications which are based
on compounds that are made by living cells.
At this time we know of no other therapeutic compound that
modulates both the Innate and Adaptive immunity. It is our opinion
that the peptide, Infeperium, is a major breakthrough!
Innate immunity refers to nonspecific defense mechanisms that come into
play immediately or within hours of an antigen's appearance in the body.
These mechanisms include physical barriers such as skin, chemicals in the
blood, and immune system cells that attack foreign cells in the body.
Adaptive immunity refers to antigen-specific immune response.
The adaptive immune response is more complex than the innate. The
antigen first must be processed and recognized. Once an antigen has been
recognized, the adaptive immune system creates an army of immune cells
specifically designed to attack that antigen.
Infeperium started into development for commercial use for humans in
February of 2015. Before then, it had been in development and testing,
under Compassionate Use Waivers, for over 10 years. The patient success
of these treatments, in cases ranging from chronic plaque psoriasis, lyme
disease, diabetic wounds, and other non-treatable diseases led to the
commercial release in several countries outside of the United States. The
genesis for Infeperium is a USDA approved immunomodulator for domestic
animals that has the same active ingredient as Infeperium.
In a recent test our Dr. Ken Willeford in association with TriMetis, designed
a salmonellosis challenge model to assess the efficacy of Infeperium along
with the synthesized peptides. On Day 6 of the study the test observed
100% mortality in the Control and Peptide Treated groups but observed a
significant 56% survival rate in the Infeperium treated group. Ken states,
"The observation that Infeperium provides immunomodulatory effects is
FANTASTIC and gives us something more to build on. It confirms our
rationale for its use in human conditions and gives us a center piece to
construct a research platform around."
Infeperium is approved for human use in research for homeopathic
treatment in Mexico and South Africa.
We expect, when fully approved and available on the market, that treatment with Infeperium of Traditional Therapies for Medical Conditons can be done more effective and at a fraction of their cost.
This includes, but is not limited to:
- Diabetic Wound Care
- Diabetes related surgical amputations
- Multiple Sclerosis
- Brain Cancer
- Lung Cancer
- Prostate Cancer
- Cervical Cancer
- Pancreatic Cancer
- Epstein-Barr Virus (EBV)
- Crohn's Disease
- Irritable Bowel Syndrome
- Ulcerative Colitis
- And many more...
To see a Cost Study of Traditional Therapies for Medical Condition that can be treated with Infeperium click here.
Infeperium is presently made according to the most rigid standards of Current Good
Manufacturing Practices (cGMP).
The active ingredient in Infeperium has already met the rigorous standards for Veterinary use and it is approved for animal prescription under the USDA!
We believe Infeperium to be a new category of drug that may be characterized as a
Biological Response Modifier and an "Immunomodulator". We believe that many
disease pathologies that affect individuals are the result of an over-active immune
system. Specifically, when a viral agent begins to adversely affect an individual's cells,
the immune system frequently becomes overactive, which destroys the viral agent but
also injures surrounding healthy cell structures. We believe other disease pathologies
suppress an individual's immune system, which allows other diseases and agents to kill
healthy cells. Although research is always ongoing, the product in its present form is
complete. Research has concluded that Infeperium regulates an individual's immune
system to prevent it from both over-reacting and under-reacting to a viral invasion of an
individual's body systems. We believe that Infeperium contains a number of unique
peptide or lipopeptide molecules which may neutralize viral pathogens and their
inhibitory properties by activation of a cytokine system. This, in turn, will enhance an
individual's cell mediated immunity and augment the individual's humoral immune
system possibly by eliminating negative inhibitory cytokine factors and pathogenic freefloating organisms, while simultaneously sparing normal and healthy cells.
Our objective is the continued development of Infeperium and its cognates and variants
for treatment of multiple medical conditions.
- Infeperium has been found to rapidly affect the expression of proteins involved in
transcription/translation/and post-translational events (folding via chaperones and
disulfide linkages). The key to the effectiveness of Infeperium is that it is not a pathogen
or a foreign agent used to provoke an immune response, but is a small molecular
weight protein found in healthy mammals that is an immune modulating signaling
- Infeperium regulates Interferon Inducible Proteins - regulation of macrophage,
microbacteriocidal activity and viral activity, identification and regulated apoptosis of
mutated cellular activity.
- Infeperium upregulates the IL-10 shut off switch for chronic inflammation, while
maintaining acute inflammation pathways.
- Infeperium restores proper cell and chemical messaging pathways
- Infeperium protects from oxidative stress by proper balance of Reactive Oxygen
Species (ROS) and Wound Repair through specified angiogenesis.
- Infeperium restores proper and amplifies Cytokine cascades.
The following illustration demonstrates the immunomodulating cascade and the enhancement of Macrophage, Cytokine activity, TNF-a, and NK cells, as well as the up-regulating and down-regulating of IL-6, IL-10, IL-12, GM-CSF and IFN-a.
Click here to learn more about the Protocols and Procedures for the Administration of Infeperium
A Major Breakthrough in Immunotherapy
We have a number of breakthrough immunomodulators and biological
response modifiers that have dramatic effects on stopping the course of degenerative
disease and reenergizing the bodies own defense mechanisms to bring it into
homeostasis (optimum health). Our proven medical protocol includes a 3 phase
approach to eradication of disease and restoration of homeostasis. the goal of this
protocol is not to "take this pill once a day for the rest of your life". But through
breakthrough therapeutics, optimum nutrition and immune surveillance bring the patient
to the health once enjoyed and a quality of life reestablished.
Immunotherapy and Immunomodulators:
Immunotherapy is the treatment of disease by inducing, enhancing or suppressing an
Immune Response. Jedd Wolchok MD summed up Immunotherapy just last year in
response to Immunotherapy being Science Magazines 2013 Breakthrough of the
Year. "10 years ago Immunotherapy was almost in the category of snake oil. A few
years ago it was stated that Immunotherapy can work. Now Immunotherapy has
entered the main stream."
James T. Allison, PhD, professor and Chair of Immunology at the MD Anderson and the
Cancer Research Institute (CRI) has received the prestigious Tang Prize, the Louisa
Gross Horwitz Prize and the Harvey Prize, all in 2014 for his work on CTLA-4 as an
antibody inhibitor in many treatment resistant cancers with amazing survival statistics.
Work in CTLA-4 & PD-1 also called "immune check point therapies" are the only two
presently approved FDA ImmunoTherapy agents so far.
Specificity. T-cells recognize peptides, which are short chain biological molecules that
are produced by every cell category including virus, bacteria, cancer/mutations. T-cells
can recognize them and can destroy them, and most importantly they have the following
two important elements.
First, Memory. As T-cells destroy pathogens, which are biological or environmental
invaders which produce abnormal cells, they go through 3 phases: expansion,
contraction and memory.
- Expansion is when the T-cells multiply to overwhelm the attacker, including
- Contraction is when they diminish due to program cell death after the attacker is
- Memory is a multiplication of cells that remember the genetic code of the attacker.
Memory cells proliferate and circulate through the body standing ready to attack.
Second, Adaptability. Cancerous tumors, viruses and bacteria, can mutate and alter
themselves in order to evade various medical therapies. Cancer alone has 9 resistant
mechanisms used to trick, hide and survive. So called present "Standard of Care
Therapies" which use in large measure synthetically produced drugs frequently harmful
to the body, but can't adapt fast enough to counteract and destroy the mutation
capabilities of cancer cells, bacteria and viruses. However, T-cell antigen receptors can.
They adapt and respond as quickly as the pathogens, because they can combine and
alter themselves as many 10 to the 15th power in different combinations. The
stimulation of the T-cells is a natural response of the body's immune system to the
injection of our breakthrough therapies. This is the key to the why and
how of immunotherapy.
An immunomodulator is a substance that either suppresses or activates the body's
immune response. These substances are separated into two groups:
immunosuppressants and immune activators. Immunosuppressants inhibit the body's
natural immune response, while immune activators generally condition or reprogram it
to target a specific disease-causing agent.
Immunomodulators can be produced in synthetic form or naturally in the body.
Cytokines are examples of innate immune mediators. Synthetic versions are available in
either immunosuppressant or immune activator forms. A suppressant immunomodulator
works by inhibiting the activation of critical immune system agents such as calcineurin
and the formation of thymus cells (T-cells) and antibodies. In comparison, an activating
immunomodulator uses the process of adaptive immunity to recondition lymphocytes
and T-cells to kill known pathogens or tumor cells.
As an immunomodulator, our active ingredient is one of the few
molecules that affects and modulates both the innate and adaptive immune
systems without negative side effects, as well as modulating from either
activation or suppression immunotherapy depending on what the body needs.
Cyclosporine and methotrexate are commonly used synthetic immunosuppressors.
Methotrexate is used in patients with autoimmune ailments. Lupus and rheumatoid
arthritis are examples of autoimmune disorders that cause the patient's body to attack his or her own cells. Eventually the targeted cells and tissue become damaged after
The process of organ rejection is similar to autoimmune dysfunction, except the immune
system targets the transplanted organ rather than the body's own cells. Organ
transplant recipients take suppressant drugs such as cyclosporine, tacrolimus and
sirolimus to prevent organ rejection. Nearly all transplant recipients, except a rare few,
must adhere to a strict daily regime that involves taking these medications for life. Not
taking the medications as prescribed will almost always induce organ rejection, which
could lead to death. Due to the medication's toxic side effects, immuno-suppressors
should only be used in cases of severe autoimmune dysfunction or organ
transplantation. Ethogen's Breakthrough Therapeutic will be investigated in the near
future for organ transplant anti-rejection and avoidance graft-versus-post disease
Immunomodulators that activate the immune system include vaccines and cancer
immunotherapy. Vaccines work by exposing the patient to weakened or inactive forms of
certain bacteria and viruses. The immune system then adapts by producing antibodies
that are programmed to immediately kill the introduced pathogen once it re-enters the
body, which is called adaptive immunity.
Cancer immunotherapy is very similar to pathogen vaccination. The difference between
the two therapies is the agent in which adaptive immunity is induced. Vaccines use
microorganisms, while cancer immunotherapy uses microorganisms and enhanced
immune cells. Microorganism-based cancer immunotherapies are used to combat some
forms of cervical and liver cancers caused by viruses. A cell-based immunomodulator,
on the other hand, uses enhanced immune cells such as cytotoxic T lymphocytes
(CTLs), dendritic cells (DC) and natural killer cells (NK cells) to target and destroy the
patient's cancerous cells.
To read more about the Science behind Infeperium click here.
The above information is provided by the developers of Infeperium, and is exclusive to Medicus LLC for their negotiations, for research purposes only, with representatives of the Veterans Administration, and certain pre-approved European and US Health providers and Bio/Pharma Companies solely! Infeperium is a non-FDA approved treatment and is not available in the United States.